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  • Innovative Methods for Rare Disease Drug Development
    Innovative Methods for Rare Disease Drug Development

    In the United States, a rare disease is defined by the Orphan Drug Act as a disorder or condition that affects fewer than 200,000 persons.For the approval of "orphan" drug products for rare diseases, the traditional approach of power analysis for sample size calculation is not feasible because there are only limited number of subjects available for clinical trials.In this case, innovative approaches are needed for providing substantial evidence meeting the same standards for statistical assurance as drugs used to treat common conditions.Innovative Methods for Rare Disease Drug Development focuses on biostatistical applications in terms of design and analysis in pharmaceutical research and development from both regulatory and scientific (statistical) perspectives.Key Features: Reviews critical issues (e.g., endpoint/margin selection, sample size requirements, and complex innovative design). Provides better understanding of statistical concepts and methods which may be used in regulatory review and approval. Clarifies controversial statistical issues in regulatory review and approval accurately and reliably. Makes recommendations to evaluate rare diseases regulatory submissions. Proposes innovative study designs and statistical methods for rare diseases drug development, including n-of-1 trial design, adaptive trial design, and master protocols like platform trials. Provides insight regarding current regulatory guidance on rare diseases drug development like gene therapy.

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  • Innovative Practices in Early English Language Education
    Innovative Practices in Early English Language Education

    This book shines a light on novel and less familiar domains of early English language education for children aged 3 to 12, in mainstream and out-of-school settings.Enveloping the volume is the making of creative connections to wider educational philosophies which extend beyond the confines of a narrow linguistic lens.In reconciling the theory-practice divide in English language education, each chapter presents a synthesis of research issues leading to a practical showcase of ideas. Organised in two main parts, the first focuses on innovations within classroom practice, curriculum development, and child-centred assessment, exploring areas which have either received insufficient attention and/or have been reimagined through fresh perspectives.The second part explores innovations in pre- and in-service teacher education contexts and focuses on lesser-known and/or underexplored topics, including bridging general and language education, multilingualism, in-depth learning, metacognition,and pragmatics.This is a timely publication for teacher educators and practitioners alike.

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  • Comprehensive Healthcare Simulation:  Operations, Technology, and Innovative Practice
    Comprehensive Healthcare Simulation: Operations, Technology, and Innovative Practice

    This practical guide provides a focus on the implementation of healthcare simulation operations, as well as the type of professional staff required for developing effective programs in this field.Though there is no single avenue in which a person pursues the career of a healthcare simulation technology specialist (HSTS), this book outlines the extensive knowledge and variety of skills one must cultivate to be effective in this role.This book begins with an introduction to healthcare simulation, including personnel, curriculum, and physical space.Subsequent chapters address eight knowledge/skill domains core to the essential aspects of an HSTS.To conclude, best practices and innovations are provided, and the benefits of developing a collaborative relationship with industry stakeholders are discussed.Expertly written text throughout the book is supplemented with dozens of high-quality color illustrations, photographs, and tables.Written and edited by leaders in the field, Comprehensive Healthcare Simulation: Operations, Technology, and Innovative Practice is optimized for a variety of learners, including healthcare educators, simulation directors, as well as those looking to pursue a career in simulation operations as healthcare simulation technology specialists.

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  • Innovative Teaching and Learning Practices in Higher Education
    Innovative Teaching and Learning Practices in Higher Education

    Thelatest volume in the Learning in Higher Education series, Innovative Teaching and Learning Practices in Higher Education introducesthe reader to a number of inspiring transformative educational practices.Itexplores in depth what has motivated these teachers to transform theirteaching, how they went about doing it, and what the results were for theirstudents in terms of learning and engagement.The innovative practices in the book centrearound three types of innovations:· Technology-based · Simulation-based · Practice-based Innovative Teaching and Learning Practices in HigherEducation takes a pedagogical, procedural, and practicalapproach to the development of innovative teaching and learning practices.Theauthors, who are university teachers themselves, focus on encouraging,empowering and enabling fellow teachers to develop, design, and implement newand innovative teaching and learning practices for the improvement of studentengagement and student learning. The book describes teaching and learning innovations in terms of thecomplex links between teaching practices and underlying theories andphilosophies of learning.Showcasing innovative practices from across differentfields of science, the book is cross-disciplinary and inclusive.

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  • Was the development of innovative car technology once hindered in East Germany?

    Yes, the development of innovative car technology was hindered in East Germany due to the country's centralized and state-controlled economy. The government's focus on producing standardized vehicles for the masses limited the ability of car manufacturers to invest in research and development for innovative technology. Additionally, the lack of competition and access to international markets further restricted the advancement of car technology in East Germany. It was only after the reunification of Germany in 1990 that the automotive industry in the former East Germany began to modernize and catch up with Western standards.

  • What does innovative mean?

    Innovative means introducing new ideas, methods, or technologies to create something original and groundbreaking. It involves thinking outside the box and finding creative solutions to problems. An innovative approach often leads to improvements, advancements, and progress in various fields such as technology, science, business, and design.

  • What is an innovative product?

    An innovative product is a new or significantly improved product that offers unique features, benefits, or functionalities that set it apart from existing products in the market. It often involves the use of new technologies, materials, or design concepts to address a specific need or solve a problem in a novel way. Innovative products can disrupt industries, create new markets, and drive growth for companies by providing customers with something they didn't even know they needed.

  • What is an innovative business idea?

    An innovative business idea is a unique concept or approach that solves a problem in a new or creative way. It involves thinking outside the box and coming up with a fresh perspective on how to address a market need or opportunity. Innovative business ideas often disrupt traditional industries or introduce new products or services that revolutionize the way things are done. These ideas have the potential to create value, drive growth, and differentiate a business from its competitors.

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  • Using Innovative Knowledge Management Tools for Information Technology Development, Acquisition, and Integration in the United States Army
    Using Innovative Knowledge Management Tools for Information Technology Development, Acquisition, and Integration in the United States Army


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  • Humanizing Higher Education through Innovative Approaches for Teaching and Learning
    Humanizing Higher Education through Innovative Approaches for Teaching and Learning

    As the demand for quality education grows, whilst resources are limited, innovative pedagogy is the only solution that can bridge both scarcity and quality.This edited collection showcases how innovative approaches to teaching and learning have become the need of the hour in higher education. How might new technologies and a fresh take on curriculum design create a sufficient impact on learners? Pouring renewed emphasis onto the practice of innovative pedagogy, the authors chronicle the success stories of fresh interventions, and demonstrate the potential impact of re-inventing the learner-centered approach.With insight from academics around the world, including action-based models, the authors address the challenges which they faced while implementing new and sometimes radical methods, and provide a roadmap for future change.Pooling a wealth of experience on how to create an efficient learning environment in today’s competitive world, this book prepares educators, policymakers and other stakeholders to embrace transformational change within their institutions.

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  • Innovative Institutions, Public Policies And Private Strategies For Agro-enterprise Development
    Innovative Institutions, Public Policies And Private Strategies For Agro-enterprise Development

    In an effort to promote agro-enterprises and agro-industries as viable forms of inclusive development, the Food and Agriculture Organization of the United Nations (FAO) and The Cornell International Institute for Food, Agriculture and Development (CIIFAD) in collaboration with the International Association of Agricultural Economists (IAAE), organized an international symposium on the topic "Innovative Institutions, Public Policies, and Private Strategies for Inclusive Agro-Enterprise Development", as part of the Triennial Meetings of the IAAE held in Foz do lguacu, Brazil, in August 2012.This book contains the major papers presented at the symposium, which feature a wide range of country and regional experiences and examine the influence of markets and technology transfer to agro-enterprises on food security, poverty, and economic growth.The contributions also identify alternative market access strategies for sustainable economic development.This volume will enrich existing knowledge of agro-enterprises as a channel for promoting inclusive growth and reducing poverty levels across developing and emerging markets.

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  • Transformative Practice in Higher Education : Innovative Approaches to Teaching and Learning
    Transformative Practice in Higher Education : Innovative Approaches to Teaching and Learning

    This insightful book transforms crisis reflections into longer term guidance for a responsive, engaged pedagogy within contemporary higher education. In recent years, higher education institutions worldwide have seen a seismic shift that has compelled them to rapidly transition to online and blended learning models.This book captures the ingenuity and resilience of educators who not only weathered the storm but emerged from it with innovative practices that have permanently transformed the landscape of teaching and learning in universities. Through interdisciplinary accounts and scholarly perspectives across diverse disciplines and geographies, it highlights care, creativity, and resilience in practices that build community, support learners and foster engaged learning.Each chapter offers enduring lessons for learner-centred, responsive pedagogy, detailing innovations that practitioners permanently integrated across delivery formats. This key title is written for higher education practitioners across the globe, whether they are teaching in the context of a subject discipline or identify themselves as blended or integrated professionals.Its insights will provide inspiration, guidance, and points for reflection for all those who wish to engage with critical pedagogies and long-term transformation in contemporary higher education.

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  • How can a country become innovative?

    A country can become innovative by investing in education and research, fostering a culture that values creativity and entrepreneurship, and providing support for startups and small businesses. Encouraging collaboration between academia, industry, and government can also help drive innovation. Additionally, creating policies that incentivize innovation, such as tax breaks for research and development activities, can further stimulate creativity and technological advancement within a country.

  • Why is this community so innovative?

    This community is so innovative because it fosters a culture of collaboration, creativity, and forward-thinking. The members of this community are encouraged to think outside the box, take risks, and pursue new ideas. There is a strong emphasis on learning and development, as well as a willingness to embrace change and adapt to new technologies and trends. Additionally, the community benefits from a diverse range of perspectives and expertise, which leads to a rich exchange of ideas and innovative solutions.

  • Why are these people always more innovative?

    These people are always more innovative because they are open-minded and willing to think outside the box. They are constantly seeking new solutions and approaches to problems, and are not afraid to take risks. They also have a strong drive to continuously improve and find better ways of doing things. Additionally, they are often well-connected and able to collaborate with others to generate new ideas and bring them to fruition.

  • Is the T-shirt beautiful and innovative?

    The beauty and innovation of a T-shirt is subjective and can vary from person to person. Some may find a T-shirt beautiful and innovative if it features unique designs, patterns, or materials, while others may prefer more classic and simple styles. Ultimately, whether a T-shirt is considered beautiful and innovative depends on individual tastes and preferences.

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